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zur Vergrößerungsansicht des Bildes: Covergrafik J. Am. Chem. Soc. 2018, 140

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64) Y. Ni; J. Lebelt; M. Barp; F. Kreuter; H. Buttkus; J. Jin; M. Kretzschmar; R. Tonner-Zech; K. Asmis; T. Gulder; Hexafluorophosphate-Triggered Hydrogen Isotope Exchange (HIE) in Fluorinated Environments: A Platform for the Deuteration of Aromatic Compounds via Strong Bond Activation; Angew. Chem. Int. Ed. 2024; 10.1002/anie.202417889. Fulltext 

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©Wiley

63)  J. P Marciniszyn; M. Kretzschmar; T. Gulder; Synthesis of 1-Iodo-n-Heteroatom-Functionalized Alkanes (n ≥2) by Addition across C—X (X = O, N, S) or C—C Bonds (Update 2024); Science of Synthesis, Knowledge Updates 2024; 10.1055/sos-SD-135-00236. Fulltext

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©Thieme

62) S. Schmidt; H. Westphal; S. Lama; M. Polack; C. Weise; T. Oestereich; R. Warias; T. Gulder; D. Belder; Development of an Automated Platform for Monitoring Microfluidic Reactors through Multi-Reactor Integration and Online (Chip-)LC/MS-Detection; React. Chem. Eng. 2024; 10.1039/d4re00004h. Fulltext

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©RSC

61) P. Zeides; K. Bellmann-Sickert; R. Zhang; C. Seel; V. Most; C. Schoeder; M. Groll; T. Gulder; Unraveling the Molecular Basis of Substrate Specificity and Halogen Activation in Vanadium-Dependent Haloperoxidases; ChemRxiv 202310.26434/chemrxiv-2023-7l30h. Fulltext

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©ChemRxiv

60) A. Arnold; J. Binder; M. Kretzschmar; T. Gulder; Alkene versus Aryl Chlorination in Asymmetric Hypervalent Iodine Catalysis: A Case Study; Synlett 2023; 10.1055/a-2201-7326. Fulltext 

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©Thieme

59) R. C. Epplin; T. Gulder; Enyne difluorination; Nat. Chem. 2023; 10.1038/s41557-023-01352-5. Fulltext 

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©Springer

58) P. Zhao; W. Wang; T. Gulder; Hypervalent Fluoro-iodane-Triggered Semipinacol Rearrangements: Synthesis of α-Fluoro Ketones; Org. Lett. 202325; 6560-6565. Fulltext 

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©ACS

57) J. Matysik; L. Gerhards; T. Theiss; L. Timmermanns; P. Kurle-Tucholski; G. Musabirova; R. Qin; F. Ortmann; I.A. Solov'yov; T. Gulder; Spin Dynamics of Flavoproteins; Int. J. Mol. Sci. 202324, 8218. Fulltext

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©MDPI

56) J. Binder; A. Biswas; T. Gulder; Biomimetic Chlorine-Induced Polyene Cyclizations harnessing Hypervalent Chloroiodane-HFIP Assemblies; Chem. Sci. 2023, 14, 3907-3912. Fulltext


55) A.M. Arnold; P. Dullinger; A. Biswas; C. Jandl; D. Horinek; T. Gulder; Enzyme-like Polyene Cyclizations Catalyzed by Dynamic, Self-Assembled, Supramolecular Fluoro Alcohol-Amine Clusters; Nat. Commun. 2023, 14, 813. FULLTEXT

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©Springer

54) M. Kretzschmar; T. Gulder; Discovering the Site-Selective Umpolung of Ketones triggered by Hypervalent Fluoro Iodanes – Why Investigating Side Reactions Matters!; Synlett 2022, 34, 405 - 413. FULLTEXT

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©Thieme

53) J. Lazic; S. S. Bogojevic; S. Vojnovic; I. Aleksic; D. Milivojevic ; M. Kretzschmar; T. Gulder; M. Petkovic; J. Nikodinovic-Runic; Synthesis, Anticancer Potential and Comprehensive Toxicity Studies of Novel Brominated Derivatives of Bacterial Biopigment Prodigiosin from Serratia marcescens ATCC 27117; Molecules 2022, 27, 3729. FULLTEXT

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©MDPI

52) A. Das; C. Weise; M. Polack; R. D. Urban; B. Krafft; S. Hasan; H. Westphal; R. Warias; S. Schmidt; T. Gulder; D. Belder; On-the-Fly Mass Spectrometry in Digital Microfluidics Enabled by a Microspray Hole: Toward Multidimensional Reaction Monitoring in Automated Synthesis Platforms; J. Am. Chem. Soc. 2022, 144, 10353–10360. FULLTEXT

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©ACS

51) P. D'Agostino, C. J. Seel, X. Ji, T. Gulder, T. A. M. Gulder; Biosynthesis of cyanobacterin, a paradigm for furanolide core structure assembly; Nat Chem Biol 2022, 18, 652 – 658. FULLTEXT

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©Springer Nature

50) D. Stierli, M. Eberle, C. Lamberth, O. Jacob, D. Balmer, T. Gulder; Quarternary a-cyanobenzylsulfonamides: a new subclass of CAA fungicides with excellent anti-Oomycetes activity; Bioorg. Med. Chem. 202130, 115965. Fulltext

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©Elsevier

49) M. Busse, J. P. Marciniszyn, S. Ferstl, M. A. Kimm, F. Pfeiffer, T. Gulder; 3D‐Non‐Destructive Imaging through Heavy Metal‐Eosin Salt Contrast Agents; Chem. Eur. J. 202127, 4561 - 4566. Fulltext

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©Wiley

48) G. M. Kiefl; T. Gulder; α-Functionalization of Ketones via a Nitrogen Directed Oxidative Umpolung; J. Am. Chem. Soc. 2020142, 20577–20582. Fulltext

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47) A. G. Collar, T. Gulder; Peptidic catalysts for macrocycle synthesis; Science 20196472, 1454. Fulltext

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46) C. J. Seel, T. Gulder; Biocatalysis Fueled by Light: On the Versatile Combination of Photocatalysis and Enzymes; ChemBioChem 201915, 1871-1897. Fulltext

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45) A. Andries-Ulmer, C. Brunner, J. Rehbein, T. Gulder; Fluorine as a Traceless Directing Group for the Regiodivergent Synthesis of Indoles and Tryptophans; J. Am. Chem. Soc. 2018140, 13034-13041. Fulltext (with cover picture)

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©ACS

44) C. J. Seel, A. Králík, M. Hacker, A. Frank, B. Koenig, T. Gulder; Atom‐Economic Electron Donors for Photobiocatalytic Halogenations; ChemCatChem 201810, 3960-3963. Fulltext

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©Wiley

43) G. K. Murphy, T. Gulder; Hypervalent Iodine Fluorination for Preparing Alkyl Fluorides (stoichiometrically and catalytically) in Synthetic Organofluorine Chemistry (Ed. J. Hu, T. Umemoto) 2018, Springer. Fulltext

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42) A. M. Arnold, A. Pöthig, M. Drees, T. Gulder; NXS, Morpholine, and HFIP: The Ideal Combination for Biomimetic Haliranium-induced Polyene Cyclizations; J. Am. Chem. Soc. 2018140, 4344–4353. Fulltext (with cover picture; highlighted as JACS Spotlight)

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©ACS

41) C. Brunner, A. Andries-Ulmer, G. M. Kiefl, T. Gulder; Hypervalent Fluoroiodane-triggered Synthesis of Fluoro-Azabenzoxazepines and Azaindoles; Eur. J. Org. Chem. 2018, 2615-2621. Fulltext (VIP article)

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40) A. Andries-Ulmer, T. Gulder; Halogenation and Halocyclization of Alkenes; Science of Synthesis: Catalytic Oxidation in Organic Synthesis20171, 389-428. Fulltext

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@Thieme

39) R. Seupel, B. Hertlein-Amslinger, T. Gulder, P. Stawski, M. Kaiser, R. Brun, Reto, G. Bringmann; Directed Synthesis of All Four Pure Stereoisomers of the N,​C-​Coupled Naphthylisoquinoline Alkaloid Ancistrocladinium A; Org. Lett. 201616, 6508-6511. Fulltext

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©ACS

38) A. Frank, C. J. Seel, M. Groll, T. Gulder; Characterization of a Cyanobacterial Haloperoxidase and Evaluation of its Biocatalytic Halogenation Potential; ChemBioChem 201617, 2028-2032. Fulltext

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37) S. V. Kohlhepp, T. Gulder; Hypervalent Iodine(III) Fluorinations of Alkenes and Diazo Compounds: New Opportunities in Fluorination Chemistry; Chem. Soc. Rev. 201645, 6270-6288. Fulltext (invited for 2016 Emerging Investigator Edition)

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©RSC

36) C. Patzelt, A. Pöthig, T. Gulder; Iodine(III)-Catalyzed Cascade Reactions Enabling a Direct Access to  β-Lactams and α-Hydroxy-β-amino Acids; Org. Lett. 201616, 3466-3469. Fulltext

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©ACS

35) M. Stodulski, S. V. Kohlhepp, G. Raabe, T. Gulder; Explorations on the Bis(thio)urea-Catalyzed Stereoselective Synthesis of Marinopyrrole A; Eur. J. Org. Chem. 201612, 2170-2176. Fulltext

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34) A. M. Arnold, A. Ulmer, T. Gulder; Advances in Iodine(III)-Mediated Halogenations: A Versatile Tool to Explore new Reactivities and Selectivities; Chem. Eur. J. 201622, 8728-8739. Fulltext (Hot Paper with cover)

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33) A. Ulmer, C. Brunner, A. M. Arnold, A. Pöthig, T. Gulder; A Fluorination/Aryl Migration/Cyclization Cascade for the Metal-free Synthesis of Fluoro Benzoxazepines; Chem. Eur. J. 201622, 3660-3664. Fulltext (Hot Paper, with cover picture, highlighted in Chem. Views Fulltext)

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32) A. Ulmer, M. Stodulski, S. V. Kohlhepp, C. Patzelt, A. Pöthig, W. Bettray, T. Gulder; Iodine(III) Catalyzed Rearrangements of Imides: A Versatile Way to α,α-Dialkylated α-Hydroxy Carboxylamides; Chem. Eur. J. 201521, 1444-1448. Fulltext

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31) H. Aldemir, S. Kohlhepp, T. Gulder, T.A.M. Gulder; On the Structure of a Putative Fluorinated Natural Product from Streptomyces sp. TC1J. Nat. Prod. 201477, 2331-2334. Fulltext

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©RSC

30) T. Gulder, T.A.M. Gulder; Biosynthesis in a Test Tube; Nachr. Chem. 201462, 1081-1084.


29) T. Gulder, T.A.M. Gulder; Hydrofunctionalizations with Unusual Regioselectivity; Nachr. Chem. 201462, 869-872.


28) T. Gulder, T.A.M. Gulder; Chemistry in Stereo: the 49th Bürgenstock Conference; Angew. Chem. Int. Ed. 201453, 9418–9420


27) T. Gulder, T.A.M. Gulder; A Sesquiterpene against Forgetfulness; Nachr. Chem. 201462, 765-768.


26) T. Gulder, T.A.M. Gulder; H as Leaving Group; Nachr. Chem. 201462, 534-537.


25) M. Stodulski, A. Goetzinger, S. V. Kohlhepp, T. Gulder; Halocarbocyclization versus Dihalogenation: Substituent directed Iodine(III) catalysed Halogenations; Chem. Commun. 201450, 3435-3438. Fulltext

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©RSC

24) T. Gulder, T.A.M. Gulder; Enantioselective Fluorocyclization; Nachr. Chem.2014, 62, 39-42.


23) M. Stodulski, T. Gulder; Nanoparticles and Peptides – a Fruitful Liaison for Biomimetic Catalysis; Angew. Chem.2012124, 11364-11366; Angew. Chem., Int. Ed. 2012, 51, 11202-11204. Fulltext

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22) D. C. Fabry, M. Stodulski, S. Hoerner, T. Gulder; Metal-free Synthesis of 3,3-Disubstituted Oxoindoles via Iodine(III)-catalyzed Bromocarbocyclizations; Chem. Eur. J. 201218, 10834-10838. Fulltext

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21) T. Gulder, P. S. Baran; Strained Cyclophane Natural Products: Macrocyclization at its Limits; Nat. Prod. Rep.201229, 899-934. Fulltext

 

20) A. Cecil, C. Rikanović, K. Ohlsen, C. Liang, J. Bernhardt, T. A. Oelschlaeger, T. Gulder, G. Bringmann, U. Holzgrabe, M. Unger, T. Dandekar; Modelling Antibiotic and Cytotoxic Effects of the Dimeric Isoquinoline IQ-143 on Metabolism and its Regulation in S. aureus, S. epidermidis and Human Cells; Gen. Biol. 201112, r24. Fulltext

 

19) G. Bringmann, T.A.M. Gulder, T. Gulder; Asymmetric Synthesis of (M)-2-Hydroxymethyl-1-(2-hydroxy-4,6-dimethylphenyl)naphthalene via a Configurationally Unstable Biaryl Lactone - Discussion Addendum; Org. Synth. 201188, 70.  Fulltext

 

18) G. Bringmann, T. Gulder, T.A.M. Gulder, M. Breuning; Atroposelective Total Synthesis of Axially Chiral Biaryl Natural Products; Chem. Rev. 2011111, 563. Fulltext

 

17) A. Jindaprasert, S. Samappito, K. Springob, J. Schmidt, T. Gulder, W. De-Eknamkul, G. Bringmann, T. M. Kutchan; In Vitro Plants, Callus and Root Cultures of Plumbago indica and Their Biosynthetic Potential for Plumbagin; King Mongkut´s Agro-Ind. J. 20102, 53-56.

 

16) G. Bringmann, S. K. Bischof, S. Müller, T. Gulder, C. Winter, A. Stich, H. Moll, K. Baumann, R. Brun; QSAR Guided Synthesis of Simplified Antiplasmodial Analogs of Naphthylisoquinoline Alkaloids; Eur. J. Med. Chem.201045, 5370-5383. Fulltext

 

15) G. Bringmann, T. Gulder, B. Hertlein, Y. Hemberger, F. Meyer; Total Synthesis of N,C-coupled Naphthylisoquinoline Alkaloids; J. Am. Chem. Soc. 2010132, 1151-1158. Fulltext

 

14) A. Ponte-Sucre, T. Gulder, T.A.M. Gulder, G. Vollmers, A. Stich, G. Bringmann, H. Moll; Morphological Changes Induced by Arylisoquinolines in Leishmania major Correlate with Compound Accumulation and Disposition; J. Med. Microbiol. 201059, 69-75. Fulltext

 

13) A. Ponte Sucre, T. Gulder, A. Wegehaupt, C. Albert, C. Rikanović, L. Schaeflein, A. Frank, M. Schultheis, U. Holzgrabe, G. Bringmann, H. Moll; Structure-Activity Relationship and Studies on the Molecular Mechanism of Leishmanicidal N,C-Coupled Arylisoquinolinium Salts; J. Med. Chem. 200953, 626-636. Fulltext 

 

12) G. Bringmann, T.A.M. Gulder, M. Reichert, T. Gulder; The Online Assignment of the Absolute Configuration of Natural Products: HPLC-CD in Combination with Quantum Chemical CD Calculations; Chirality 200820, 628-642. Fulltext

 

11) G. Bringmann, T. Gulder, T.A.M. Gulder; Asymmetric Synthesis of Biaryls by the 'Lactone Method' in Asymmetric Synthesis - The Essentials 2nd Edition (Eds. S. Bräse, M. Christmann), Wiley-VCH, Weinheim; 2008, 260-264.

 

10) G. Bringmann, J. Spuziak, J. H. Faber, T. Gulder, I. Kajahn, M. Dreyer, G. Heubl, R. Brun, V. Mudogo; Six New Naphthylisoquinoline Alkaloids and a Related Benzopyranone from a Congolese Ancistrocladus species Related to Ancistrocladus congolensis, Phytochemistry 200869, 1065-1075. Fulltext

 

9) G. Bringmann, Y. Haagen, T.A.M. Gulder, T. Gulder, L. Heide; Biosynthesis of the Isoprenoid Moieties of Furanonaphthoquinone I and Endophenazine A in Streptomyces cinnamonensis DSM 1042; J. Org. Chem200772, 4198-4204. Fulltext

 

8) G. Bringmann, T. Gulder, T.A.M. Gulder; Asymmetric Synthesis of Biaryls by the ‘Lactone Method’  in Asymmetric Synthesis - The Essentials (Eds. M. Christmann, S. Bräse); Wiley VCH-Verlag: Weinheim, 2006, 246-250.

 

7) G. Bringmann, T. F. Noll, T. Gulder, M. Dreyer, M. Grüne, D. Moskau; Polyketide Folding in Higher Plants: Biosynthesis of Phenylanthraquinone Knipholone; J. Org. Chem. 200772, 3247-3252. Fulltext

 

6) C. Anderle, S. Alt, T. Gulder, G. Bringmann, B. Kammerer, B. Gust, L. Heide; Biosynthesis of Clorobiocin: Investigation of the Transfer and Methylation of the Pyrrolyl-2-carboxyl Moiety; Arch. Microbiol. 2007187, 227-237. Fulltext

 

5) A. Ponte-Sucre, J. H. Faber, T. Gulder, I. Kajahn, S. E. H. Pedersen, M. Schultheis, G. Bringmann, H. Moll; Activity of Naphthylisoquinoline Alkaloids and Synthetic Analogs Against Leishmania major; Antimicrob. Agents Chemother. 200751, 188-194. Fulltext

 

4) K. Felgentreff, C. Beisswenger, M. Griese, T. Gulder, G. Bringmann, R. Bals; The Antimicrobial Peptide Cathelicidin Interacts with Airway Mucus; Peptides 200627, 3100-3106. Fulltext

 

3) G. Bringmann, I. Kajahn, S. E. H. Pedersen, M. Reichert, J. H. Faber, T. Gulder, R. Brun, S. B. Christensen, A. Ponte-Sucre, H. Moll, G. Heubl, V. Mudogo; Ancistrocladinium A and B, the First N,C-coupled Naphthyldihydroisoquinoline Alkaloids from a Congolese Ancistrocladus Species; J. Org. Chem. 200671, 9348-9356. Fulltext

 

2) G. Bringmann, T. Gulder, M. Reichert, F. Meyer, Ancisheynine, the First N,C-Coupled Naphthylisoquinoline Alkaloid: Total Synthesis and Stereochemical Investigations; Org. Lett. 20068, 1037-1040. Fulltext

 

1) W. Seefelder, N. Bartke, T. Gronauer, S. Fischer, H.-U. Humpf, Structural Studies of Sphingolipids, a Class of Chemopreventive, Compounds in Food; Functional Food: Safety Aspects, Symposium, Karlsruhe, Germany, May 5-7, 2002 (2004).

G. Bringmann, T. Gulder, U. Hentschel, F. Meyer, , H. Moll, J. Morschhäuser, A. Ponte-Sucre de Vanegas, W. Ziebuhr, A. Stich, R. Brun, W.E.G. Müller, V. Mudogo; Biofilm-inhibiting Effect and Anti-infective Activity of N,C-Linked Arylisoquinolines and the Use thereof; WO Patent US WO 2008/037482 A1, issued 03.04.2008; US Patent Application US 2010/0286198 A1, issued 11.11.2010


G. Bringmann, T. Gulder, U. Hentschel, F. Meyer, , H. Moll, J. Morschhäuser, A. Ponte-Sucre de Vanegas, W. Ziebuhr, A. Stich, R. Brun, W.E.G. Müller, V. Mudogo; Preparation of Isoquinolines as Antibacterial Coating Agents; German Patent DE 10 2006 046 922 B3 2007.11.15, issued 15.11.2007.

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